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Exosomes For Brain Health
What are Exosomes?
Exosomes are nanoparticles that come from cells and carry intracellular messages to regulate regenerative processes such as stopping inflammation and stimulating tissue repair. They may be the holy grail of anti-aging and restorative therapeutics, as well as the basis for future biologic pharmaceuticals. Numerous therapeutic applications of exosomes are being investigated, ranging from cancer detection and treatment to hair restoration and wrinkle reduction. One of the most exciting developments is the use of exosomes in preventing age-related cognitive and fitness decline and neurodegeneration.
The Benefits of Exosomes for Brain Health
Because they are nanoparticles, exosomes pass through the blood-brain barrier into the cerebrospinal fluid. Clinical researchers, including Dr. Oberg, are excited. We are collaborating with some of the leading scientists in the country by being a research site where patients can qualify to be participants in experimental neuro-regeneration and longevity studies using exosomes. For example, neurologist Sheldon Jordan, MD clinical trials with exosomes treat conditions from Parkinson’s to neuropathic pain syndromes. The Young Blood Institute filters out the bad stuff and infuses the good study (the exosomes). Dr. Oberg’s own longitudinal study results include regained motor control in quadriplegics, resolution of neurologic symptoms associated with long-haul Covid, and symptoms of anti-aging such as reversal of BPH. Results thus far look promising, and much less invasive than many treatment options.
Links to Research:
If you qualify for one of the studies using exosomes, there are some steps that you may wish to take prior to starting exosome therapy. The best responses occur when the person has taken a few weeks to optimize the body’s healing environment (healthy lifestyle, pre-treatment with IV micronutrients, anti-inflammatory diet, etc.). Your preparation protocol can be personalized during an appointment, or you can follow the 28 day Brain Health program, and any necessary pre-exosome treatments will be scheduled.
Exosomes can be administered topically or intravenously. For qualified participants, cognitive treatments start with intravenous infusions 2 weeks apart and then every 4-6 weeks until desired results are achieved. Six treatments are common, but many people stay enrolled in the studies indefinitely to continue contributing to science and to stay ahead of inevitable aging. Treatment is dose-dependent, up to a limit.
Following exosome infusions, responses vary. Some people feel euphoric or very energetic the same day. Others experience a few days of fatigue or myalgia before realizing aches and pains are gone and vitality is improving. Some people appreciate improved sleep, lessening of grey hair and wrinkles, and improved vitality over several treatments. Sensitive individuals may wish to take a dose of Benadryl before treatment.
Schedule Your Appointment
For more information regarding enrolling in our research studies of exosome therapy to improve brain health, contact VitaLab in San Diego, CA today. To begin you will meet with a study clinician who will determine if you meet eligibility criteria and are a good candidate.
What are exosomes exactly?
Exosomes are nanoparticles that come from stem cells and carry intracellular messages to regulate regenerative processes such as stopping inflammation and stimulating tissue repair. They may be the holy grail of anti-aging and restorative therapeutics, as well as the basis for future biologic pharmaceuticals. Some of the applications for which exosomes are being investigated include hair restoration & wrinkle reduction, orthopedic repair, immune modulation for COVID and chronic post-viral syndromes, neuro-regeneration, and more. What excites me most about exosomes is their potential role in preventing age-related cognitive decline, physical fitness decline, and neurodegeneration.
What are exosomes made of?
Exosomes are derived from mesenchymal stem cells which are abundant in placenta. MSC-derived exosomes are especially important as they carry intracellular messages that tell cells of all types (i.e they are pluripotent) to start repairing and regenerating.
What is exosomes Therapy?
Here are some research studies if you want to read more about the scientific basis of exosome therapy.n1. Exosome Therapy: a new frontier in regenerative medicine. 2021. PMC8100822n2. This study discussed exosome therapy in neuroregeneration: Jordan S, Pain Physician. 2020 Mar;23(2):229-233. PubMed PMID: 32214305.3 n3. This research study describes exosome therapy in skin: PMID: 29434006n4. This research study describes exosome therapy for orthopedics and osteoarthritis: PMID: 27871993n5. This study discusses exosome therapy with regard to immune modulation: PMID: 32392899n6. Nassar W, El-Ansary M, Sabry D, et al. Umbilical cord mesenchymal stem cells derived extracellular vesicles can safely ameliorate the progression of chronic kidney diseases. Biomaterials Research 2016; 20(1):21.
Are exosomes better than stem cells?
Exosomes are derived from stem cells. Bone marrow, adipose, and mesenchymal stem cells are the most common sources of exosomes. Exosomes are generally agreed to be the reason why stem cell therapies work. However, unlike stem cell therapies, exosomes are acellular and thus avoid the risk of cell therapies. Exosomes are also more reliable and consistent; they are isolated under highly controlled sterile laboratory conditions and carefully analyzed so we know the potency and sterility of each batch. In summary, exosomes seem to be better than stem cells because they are safer, more reliable, and the potency can be quantified and selected for the individuals needs.
Are exosomes FDA approved?
Exosomes are currently an unapproved therapy, which means the FDA has not yet reviewed the research on exosomes one way or the other for the treatment or cure of any specific disease or medical condition. The use of exosomes is unregulated and has not been approved or cleared by the Food and Drug Administration. Nevertheless under the supervision of a doctor, you can opt to have this treatment. As such, if you are requesting this treatment, and agree to undergo the treatment, be aware that you are undergoing a procedure that is not regulated by government agencies. If you choose to have this treatment, you will be given opportunity to ask about the risks and benefits and have all of your questions answered before you give consent.
What is exosome therapy for hair loss?
Exosomes can be used for hair restoration. Exosomes are microneedled directly into the scalp and hair line. 1 unit treats about 7-10 cm2 of scalp. It is repeated every 4-6 weeks until desired results are achieved.
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